GHK-Cu, also known as copper tripeptide-1, is a small peptide complex formed by the binding of the tripeptide glycyl-L-histidyl-L-lysine (GHK) with copper ions. This compound was originally identified in human plasma and has since become a widely studied peptide in biochemical, dermatological, and cosmetic ingredient research. Due to its simple structure and ability to bind copper ions, GHK-Cu has attracted attention in laboratories exploring peptide activity and metal-ion interactions.
GHK-Cu peptide powder is typically produced through controlled peptide synthesis followed by purification processes to obtain high purity material suitable for laboratory research. The compound is recognized for its characteristic blue color, which results from the presence of copper ions bound to the peptide chain. The relatively small molecular structure of the tripeptide allows it to dissolve in aqueous systems, making it convenient for experimental preparation and formulation testing.
In laboratory environments, peptides with stable structures and predictable behavior are often preferred for experimental work. GHK-Cu fits this requirement well because the tripeptide structure remains relatively stable under appropriate storage conditions. For this reason, it is frequently used as a reference peptide in studies related to peptide chemistry, metal ion binding, and cosmetic ingredient research.
High purity material is particularly important when working with peptide compounds. Research-grade GHK-Cu is commonly produced with a purity level above 99%, verified through analytical testing methods such as HPLC-UV. These quality control procedures help ensure that the peptide maintains consistent characteristics during laboratory experiments and formulation development.
One of the main features of GHK-Cu is its ability to bind copper ions with strong affinity. Copper plays a role in many biological and enzymatic processes, and peptide-copper complexes have been the subject of numerous studies in biochemical research. Because the GHK tripeptide can carry copper ions in a stable form, it is often examined in experiments that investigate how metal ions interact with peptides and biological systems.
Another advantage of GHK-Cu peptide powder is its relatively small molecular size. Small peptides are generally easier to dissolve and incorporate into experimental solutions, allowing researchers to work with a wide range of concentrations depending on their research design. This flexibility is useful when studying peptide stability, formulation compatibility, or molecular behavior in controlled environments.
The compound has also been frequently referenced in studies focusing on skin physiology and extracellular matrix activity. Researchers often examine how peptide-based ingredients interact with skin cells or structural proteins during laboratory testing. As a result, GHK-Cu has become one of the better known peptide materials used in early-stage cosmetic ingredient development and peptide formulation research.
Stability is another important factor when selecting peptides for research purposes. When stored under appropriate conditions, GHK-Cu peptide powder can maintain its chemical structure for an extended period. This makes it suitable for repeated laboratory testing or long-term research projects that require consistent peptide materials.
GHK-Cu peptide powder is used in several areas of laboratory research. One of the most common fields is dermatological and skin biology research. In these studies, scientists investigate how peptides interact with cellular systems, extracellular matrix components, or other molecules involved in skin physiology.
In cosmetic ingredient development, GHK-Cu is often explored during formulation testing stages. Because the peptide can dissolve in water-based systems, it may be incorporated into experimental formulations such as gels, serums, or emulsions used in laboratory studies.
Researchers can then evaluate stability, compatibility with other ingredients, and general formulation performance.
Another area where GHK-Cu is frequently used is peptide chemistry research. As a naturally occurring copper-binding peptide complex, it can serve as a model compound for studying peptide-metal interactions. This makes it useful in academic research or analytical studies that focus on molecular binding mechanisms and peptide behavior.
Some laboratories also use GHK-Cu as a reference material when developing analytical testing methods for peptides. Its well-documented structure and predictable chemical properties make it suitable for testing purification techniques, stability studies, and laboratory quality control procedures.
| Item | Description |
|---|---|
| Product Name | GHK-Cu (Copper Tripeptide-1) |
| CAS Number | 9030-95-5 |
| Purity | ≥99% |
| Appearance | Blue Powder |
| State | Solid |
| Test Method | HPLC-UV |
| Package | 100 mg per vial, 10 vials in one kit |
| Application | For Research Use Only |
| Storage | Store at 4°C, sealed and protected from light and moisture |
| Shelf Life | Retest date: 2 years under proper storage conditions |
For optimal stability, GHK-Cu peptide powder should be stored in a cool and dry environment. Refrigerated storage at approximately 4°C is generally recommended, with the material kept tightly sealed to prevent exposure to moisture and air. Direct sunlight and high temperatures should be avoided, as these conditions may gradually affect peptide stability.
When preparing experimental solutions, the peptide can be dissolved in sterile water or other suitable solvents according to the requirements of the research protocol. Standard laboratory handling practices should be followed to maintain product quality and ensure consistent experimental results.
GHK-Cu peptide powder is a well-known copper-binding tripeptide widely used in biochemical and dermatological research. Its stable structure, characteristic blue appearance, and high purity make it suitable for laboratory experiments related to peptide chemistry, skin biology studies, and cosmetic ingredient development. When produced under controlled conditions and stored properly, research-grade GHK-Cu can provide consistent performance across a wide range of scientific and formulation applications.
